Lecturer Dr. Demet ŞAYLAN

Lecturer Dr. Demet ŞAYLAN

After completing my undergraduate education at Hacettepe University, Department of Biology, I studied the relationship between Catechol-O-methyltransferase (COMT) gene polymorphism and patient response to antidepressant treatment at Ankara University Faculty of Pharmacy. I conducted studies at Brunel University of London to determine the responses to chemotherapeutics in ovarian cancer and to investigate the increased DNA repair capacity in cisplatin-resistant cells. For my Ph.D project, I joined G. Don Jones' lab at the Institute of Leicester Cancer Research Center, University of Leicester. My focus was to investigate the relationship between chemotherapy and radiotherapy resistance and abnormal activation in the hedgehog signaling pathway in glioblastoma multiforme, which is called Grade-4 brain cancer. I aim to conduct studies on detecting signaling pathways with abnormal activity in cancer and cancer stem cells.After completing my undergraduate education at Hacettepe University, Department of Biology, I studied the relationship between Catechol-O-methyltransferase (COMT) gene polymorphism and patient response to antidepressant treatment at Ankara University Faculty of Pharmacy. I conducted studies at Brunel University of London to determine the responses to chemotherapeutics in ovarian cancer and to investigate the increased DNA repair capacity in cisplatin-resistant cells. For my Ph.D project, I joined G. Don Jones' lab at the Institute of Leicester Cancer Research Center, University of Leicester. My focus was to investigate the relationship between chemotherapy and radiotherapy resistance and abnormal activation in the hedgehog signaling pathway in glioblastoma multiforme, which is called Grade-4 brain cancer. I aim to conduct studies on detecting signaling pathways with abnormal activity in cancer and cancer stem cells.